Advisee Information
Chemii Club
Courses Taught
 • FS 101
 • Chem 110
 • Chem 112
 • Chem 231
 • Chem 232
 • Chem 236
 • Chem 432
 • Chem 587
 • Chem 590
 • Chem 611/612
Inside Chemistry
Master Calendar
Organic Workshops
Pelletier Library
Registration Information
Research and CV
Schedule
Web Links

Allegheny College
Department of Chemistry
520 N. Main Street
Meadville, PA 16335
814-332-5363

Chem 432:
Carbanions in Organic Synthesis








• SSM Home


Make an Office Appointment

 
Carbanion chemistry represents an enormously important set of reactions in the organic chemist‘s arsenal, as exemplified in the total synthesis of bongkrekic acid (above), a potential apoptosis inhibitor, which involves asymmetric alkylation and anionic allyl coupling (Shindo, M.; Sugioka, T.; Umaba, Y.; Shishido, K. Tetrahedron Lett. 2004, 45, 8863).

This advanced course examines the use of carbanion techniques in total synthesis and synthetic methodology from the current literature. Related topics are also considered, such as protection/deprotection technology, stereoelectronic considerations, and other key steps in the synthetic plans.

Students contribute to the class through literature research, discussion, and in-class presentations. Credit: Two semester hours. Taught second half of the semester.

Prerequisite: Chem 232.

 


Advanced Search